Research Overview
The main aim of the group is to use Biology as inspiration for the design of functional supramolecular materials. The team has a broad expertise in the design of peptide-based self-assembled fibrillar networks and supramolecular gels. Currently, the research program is focused on developing peptide based soft materials for applications in biomimetic supramolecular catalysis, drug delivery and as biomaterials for regenerative medicine. The group has expertise in organic synthesis as well as in preparation and characterization of supramolecular materials.
Group's research interests
Synthesis and characterization of new peptide-based low molecular weight compounds.
Fundamental understanding of the self-assembly process for single- and multicomponent supramolecular materials.
Development of biocompatible and biodegradable hydrogels for application in skin drug delivery as well as materials with antimicrobial, anti-inflammatory and pro-angiogenic abilities for chronic wound healing.
Development of biomimetic materials with rheological properties amenable for 3D-printing.
Development of complex soft materials for biomimetic supramolecular catalysis.
Members
Publications
2024
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Advanced Optical Materials, 2024, 13 (4), 2402270.
Paul, S.; Adhikari, S.Das; Pareja-Rivera, C.; Masi, S.; Julián-López, B.; Martínez-Pastor, J.P.; Escuder, B.; Mora-Seró, I.
Article page: https://onlinelibrary.wiley.com/doi/10.1002/adom.202402270
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RSC Advances, 2024, 14, 15120-15128 .
Özbek, N.; Llorens-Vilarrocha, E.; Vicedo-Jover, B.; Falomir-Ventura, E.; Escuder, B.
Lysine-based non-cytotoxic ultrashort self-assembling peptides with antimicrobial activity .
Article page: https://pubs.rsc.org/en/Content/ArticleLanding/2024/RA/D3RA08883A
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Angewandte Chemie International Edition, 2024,
Paul, S.; Gayen, K.; Cantavella, P.Gil; Escuder, B.; Singh, N.
Complex Pathways Drive Pluripotent Fmoc-Leucine Self-Assemblies.
Article page: https://doi.org/10.1002/anie.202406220
2023
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ChemBioChem, 2023, e202300438.
Giménez-Hernández, B.; Falomir, E.; Escuder, B.
Effect of Hyaluronic Acid on the Self-Assembly of a Dipeptide-Based Supramolecular Gel.
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Chemical Science, 2023, 14, 8984-8999.
Adhikari, S.Das; Gualdrón-Reyes, A.F.; Paul, S.; Torres, J.; Escuder, B.; Mora-Seró, I.; Masi, S.
Article page: https://pubs.rsc.org/en/content/articlelanding/2023/sc/d3sc02955g
2021
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ACS Applied Bio Materials, 2021, 4, 935-944.
Martí-Centelles, R.; Dolz-Pérez, I.; De la O, J.; Ontoria-Oviedo, I.; Sepúlveda, P.; Nebot, V.J.; Vicent, M.J.; Escuder, B.
Two-Component Peptidic Molecular Gels for Topical Drug Delivery of Naproxen.
Article page: https://pubs.acs.org/doi/10.1021/acsabm.0c01422