Where: Saló d'actes de l'escola de doctorat
Presented by: Prof. Beatriu Escuder
Supramolecular hydrogels are formed through the self-assembly of low-molecular-weight gelators (LMWGs) in water, creating three-dimensional fiber networks via non-covalent interactions. The primary drawback of supramolecular hydrogels is their generally low mechanical strength. Therefore, the fabrication of hybrid LMWG-biopolymer materials is a useful strategy to enhance the final properties of the material. In this context, the synthesis of novel supramolecular hybrid hydrogels combining LMWGs with biopolymers for use as multicomponent biomaterials is of significant interest.
On the one hand, LMWG-polymer conjugates are prepared by synthesizing two low-molecular-weight peptide fragments that are covalently linked to the polymer, L-polyglutamic acid (PGA). On the other hand, multicomponent supramolecular hydrogels are developed. These hydrogels are formulated using biocompatible polymers such as hyaluronic acid (HA), L-polyglutamic acid (PGA), or different gelatins, which are combined with a supramolecular gelator based on dipeptides.
